The guinea pig is highly susceptible to soft tissue calcifi cation. Wulzen and Bahrs ('41) first reported a stiffness syn drome which has heen studied in detail and reviewed by van Wagtendonk and Wulzen ('50). The syndrome was characterized by stiff joints and by extensive soft tissue calcification and necrosis. A similar syndrome was reported by Hogan et al. ( '50, '54) in guinea pigs that consumed excess phosphorus. Smith et al. ('49) also observed metastatic calcification when certain diets were fed for long periods. [...]
O'Dell, B. L. et al.: Diet Composition and Mineral Balance In Guinea Pigs.
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