Roth, S.I. et al.: Animal model of human disease. Spontaneous diabetes mellitus in the New Zealand white rabbit
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Thema: Roth, S.I. et al.: Animal model of human disease. Spontaneous diabetes mellitus in the New Zealand white rabbit 04.12.12 22:42
S. I. Roth and H. H. Conaway: Animal model of human disease. Spontaneous diabetes mellitus in the New Zealand white rabbit. In: Am J Pathol. 1982 December; 109(3): 359–363.
DIABETES MELLITUS is a common disease found in humans of all ages. Recent classifications have proposed two basic forms of the disease: insulindependent diabetes mellitus (IDDM), usually seen in children, and insulin-independent diabetes mellitus (IIDM), usually associated with obesity and seen in adults.' Models similar to human diabetes mellitus have been produced in laboratory animals by a variety of methods, including viral infections, chemical agents, hormones, and antibodies.2-9 Spontaneous syndromes resembling human diabetes mellitus have also been observed in a variety of domestic and laboratory animals. 0-30 Both the spontaneous and induced diabetic animal models are being extensively studied in an effort to gain a better understanding of the etiology, pathophysiology, treatment, and cure of the human disease.
Roth, S.I. et al.: Animal model of human disease. Spontaneous diabetes mellitus in the New Zealand white rabbit