Snyder, S.H. et al.: Control of the Circadian Rhythm in Serotonin Content of the Rat Pineal Gland

Solomon H. Snyder, Mark Zweig, Julius Axelrod, Josef E. Fischer: Control of the Circadian Rhythm in Serotonin Content of the Rat Pineal Gland.
In: Proc Natl Acad Sci U S A. 1965 February; 53(2): 301–305.

Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC219511/pdf/pnas00154-0077.pdf


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Circadian rhythms have been demonstrated in mammals for a variety of biological phenomena, including running activity,' rectal temperature, plasma eosinophil and corticosterone levels, liver mitoses, and nucleic acid content. Certain of these rhythms are considered endogenous since they persist in the absence of environmental lighting." I Controlling centers within the organism for these rhythms have been sought without success. Thus adrenal-dependent rhythms in epidermal mitoses and rectal temperature persist after hypophysectomy, although their amplitude is diminished.
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