Cheeke PR et al: Toxicity of Senecio jacobaea and pyrrolizidine alkaloids in various laboratory animals and avian species

Cheeke PR, Pierson-Goeger ML: Toxicity of Senecio jacobaea and pyrrolizidine alkaloids in various laboratory animals and avian species.
In: Toxicol Lett. 1983 Sep.

Link: http://www.ncbi.nlm.nih.gov/pubmed/6665808

Zitat :

Abstract
The chronic toxicity of tansy ragwort (Senecio jacobaea) to several herbivorous laboratory animals and to chicks and turkey poults was examined by feeding the dried plant as a component of a mixed diet. Gerbils, hamsters and guinea pigs were resistant to chronic toxicity. Gerbils were highly resistant, consuming over 3500% of their body weight of the dried plant, whereas susceptible species succumb to a tansy ragwort intake of 5-20% of their body weight. Guinea pigs and gerbils were resistant to acute toxicity of injected monocrotaline, a pyrrolizidine alkaloid (PA). They were moderately resistant to acute toxicity of injected tansy ragwort alkaloids. Both chicks and turkey poults were susceptible to chronic toxicity of dietary tansy ragwort.